@Andrew
At the moment I can not find why or what could be running at 21:30 but have a few thoughts into it, Including possible outside hack attempts, as I am on a Fixed IPv4 & IPv6 and the modem is bridged mode to one NIC.

But on the VM I have running Pfsense2.6, Plex (Debian10), (Emails, dns, web) Freebsd12, Unifi (debain10), Asterisk (debian10), XenOrchestra7.4CE (Debian10).
Not running but can be spun up, Winxp64, XenOrchestra(Paid Version)

I have a replacement Nic in the mail and hope this will fix the problem, but wondering if I need to disable the onboard ones to stop the crash even if I force all to use the new ones, but hope this replacement card fixes the problems.