For me it's working without issues since it was released.
ASUS Prime X670-P , 7900X and 2x32 GB 5600 (QVL).
The realtek nic, gave me some trouble, so I move on from it to a i350-T4 temporary.
The ASUS motherboard was the only one with 3 mechancal 16x ports.
I use them with 3 cards (2xi350-T4 and 1 x520-DA2).
I left a VM for a week with 20 cores doing ML and seems to be stable.
I would prefer a more enterprise solution but I had this HW for another purpose and did some testing.,
I chose the AM5 route so I don't spend money on a dedicate x1 GPU in a headless computer. And had to deal with many issues in the BIOS settings to get things properly running.
Today I tested a Corsair 6200 MT 32-38-38 Memory, lot's of issues @ 6.2 (just XCM profile Auto). Lot's of issues, @ 6000 MT seems to be working fine.