@laszlobortel we've seen far less of this issue since my last message, not sure what made it better and when. But we're still making sure to reboot monthly (during patching, as we normally do anyways) + after live migration, and that helps. We don't use load balancing, so once a VM is staying put on one hypervisor, there is no issue. Live migration and time triggers the issue for us.
What changed in our infra is upgrade to XCP-NG 8.3 and moving to XOSTOR as shared storage. We've seen no issue with AlmaLinux 9 and CloudLinux 9 at all. They also perform better I/O wise.